Cannabidiol (CBD) was among the first plant cannabinoids to be discovered and then also erroneously predicted to be an inactive compound because researchers were looking for psychoactive aspects of the cannabis plant at the time.
Interestingly, our body produces its own cannabinoids (endocannabinoids) when it needs them.
In addition, they do not circulate in larger quantities through the bloodstream than e.g. hormones.
They are formed locally - when the wrists are twisted, they are formed only there and, according to their role, they decompose quickly.
However, when we get sick from various diseases and our system is malnourished or working at too high a pace, we need outside help - cannabinoids from cannabis.
These will help balance our endocannabinoid system over months of use.
Dr. Tanja Bagar says ours and those of cannabinoids from cannabis are signaling molecules.
This means that when something bad happens in the body, they signal you and call for help those cells that will solve the problem.
CBD showed no effect on psychoactivity, and it also turned out to have no direct effect on CB1 and CB2 receptors, which were discovered more than sixty years later.
At home:
These are the locks in our body that cannabis can affect with its key (CBD, THC…). Without them, the plant would be useless to us.
CBD acts indirectly and stimulates the body's own cannabinoid system by blocking the enzyme FAAH, which is responsible for breaking down anandamides.
Explanation:
Our bodies know how to make cannabis-like compounds (anandamide is, say, our version of CBD) to maintain balance in all of our systems. Because they can break down too quickly, we have too few of them in our body. They can help by taking CBD cannabis.
When a large amount of anandamides is present in the body, the activity of CB1 receptors and the vitality of the endocannabinoid system also increase.
CBD also binds to various other receptors in the brain, including serotonin 5HT1A (helps with antidepressant action), TRPV1 (contributes to anti-psychoactive effects), nuclear receptor PPAR-gamma (regulates gene expression) and orphan receptor GPR55 (contributes to action). against cancer and osteoprotection).
It is good to know:
Synthetic cannabinoid treatment is available on a white prescription at the Oncology Institute, where THC and CBD are mixed in a 1: 1 ratio. This cannabis is not natural and has a much worse effect on many. Then it is necessary to cut a natural preparation from the whole plant.